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Phosphatidylserine

Brain cell membrane phospholipid for memory and cortisol control

★ 4.3 / 5.0 Editors' score

Phosphatidylserine is a paid Memory Enhancement supplement — Brain cell membrane phospholipid for memory and cortisol control It offers 6 core capabilities, including FDA-qualified health claim, Reduces cortisol levels, Supports brain cell membranes. Pricing is paid, starting at $22.99/bottle. It is rated 4.3/5 in our memory enhancement directory, with its main trade-off being soy-derived versions may concern some. Phosphatidylserine is a good fit for anyone comparing memory enhancement options.

Key Facts

Category Memory Enhancement
Pricing model paid
Starting price $22.99/bottle
Rating 4.3 / 5.0
Best for Memory Enhancement
Key features 6
Last updated 2026-02-23

Overview

Phosphatidylserine (PS) is a phospholipid essential for brain cell membrane integrity and function. It's one of the few supplements with an FDA-qualified health claim for cognitive function. PS supports memory, reduces cortisol levels during stress, and helps maintain cognitive function with aging. The Sharp-PS brand is the most studied form.

Official site unavailable at our last check (July 2026) — the product may have been discontinued or rebranded.

Key Features

  • ✓ FDA-qualified health claim
  • ✓ Reduces cortisol levels
  • ✓ Supports brain cell membranes
  • ✓ Memory and recall enhancement
  • ✓ Sharp-PS branded form
  • ✓ Anti-aging cognitive support

Pros

  • ✅ FDA-qualified health claim for cognition
  • ✅ Proven cortisol reduction
  • ✅ Essential for brain cell structure
  • ✅ Well-tolerated

Cons

  • ❌ Soy-derived versions may concern some
  • ❌ Effective doses can be expensive
  • ❌ Best results at 300mg+/day

Pricing

Model: paid

Starting at: $22.99/bottle

Compare Phosphatidylserine

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Frequently Asked Questions

What is Phosphatidylserine?
Phosphatidylserine (PS) is a phospholipid essential for brain cell membrane integrity and function. It's one of the few supplements with an FDA-qualified health claim for cognitive function. PS supports memory, reduces cortisol levels during stress, and helps maintain cognitive function with aging. The Sharp-PS brand is the most studied form.
How much does Phosphatidylserine cost?
Phosphatidylserine starts at $22.99/bottle. The pricing model is paid.
What are the main features of Phosphatidylserine?
Key features include: FDA-qualified health claim, Reduces cortisol levels, Supports brain cell membranes, Memory and recall enhancement, Sharp-PS branded form, Anti-aging cognitive support.
Who is Phosphatidylserine best for?
Phosphatidylserine is a good fit for anyone comparing memory enhancement options, and is rated 4.3/5 in this category.
What are the limitations of Phosphatidylserine?
Reported trade-offs include: Soy-derived versions may concern some; Effective doses can be expensive; Best results at 300mg+/day.
What are the best Phosphatidylserine alternatives?
See our full list of Phosphatidylserine alternatives, with side-by-side ratings, pricing, and pros & cons, on the Phosphatidylserine alternatives page.

Last updated: 2026-02-23